Drake May is the standout stock-up, pacing as a top fantasy QB with a favorable matchup slate and a diversified Patriots attack that fed multiple receivers. Cam Scataboo erupted for the Giants, while Rico Dott and Chuba Hubbard kept Carolina in wins with a backfield-by-committee approach that still favored volume. The backfield reshuffles continued with Kamani Vidal taking over in San Diego’s run game, complemented by Devin Achan and Jaylen Waddle supplying steady fantasy floors for Miami.

Injury news drove waiver-wires: Puka Nacua’s London outing and Kyler Murray’s crew faced questions, while PPR-friendly targets like Demario Douglas, Stefon Diggs, and Travis Etienne remained reliable in solid matchups. The Chiefs’ Kelce-Rashii Rice stack remained a staple, and the Jets’ offense added via Joe Flacco and Bryce Young/CJ Stroud debate left managers weighing ceiling vs. risk. Deliberate pickups included Bam Knight and Cameron Johnson, with Streaks and schedules guiding who gets the edge down the stretch.

Colts win behind a versatile, identity-driven attack led by Jonathan Taylor and the multi-role Tyler Warren, who lines up as back, receiver and true tight end. Warren’s usage signals a stable floor for Colts’ fantasy managers, with Pitman and Downs providing reliable targets as Harrison Jr. leaves the game with an injury. In Arizona, Bam Knight and Michael Carter split carries in a backfield that remains a blender, while Trey McBride continues to command a solid target share and Kyler Murray’s connection to the offense remains a focal point.

Arizona’s offense leans on McBride as a reliable middle of the pack option, and the backfield’s split raises risk for streaming RBs. The upcoming matchup against Green Bay shapes the weekly outlook, with Warren’s high-usage profile and the Colts’ plan to lean on a run-first identity offering a clear path to fantasy relevance in tight-end premium formats. Injury notes and late-game shifts add volatility, but the core pieces stay actionable for managers chasing depth and upside.